English: SCREENING LIBRARY
Roles of Genomic Library

With the complete information in the library for a specific organism, researchers can perform a variety of experiments on the DNA. By doing so, they can determine the actions and interaction of separated genes along the strand. Also, they can compare the genomic library of healthy and unhealthy individuals of the same species to see where differences in genetic coding may be led to unexpected mutations.

In physical reality, a genomic library for humans is a collection of bacteria, the most common one is E. coli. The usable sequence of DNA from the human genome gets transferred and carried through the E. coli. The DNA is prepared by digesting it with a restriction enzyme. Then the target segments are inserted into the bacteria by using lambda phage. This creates a basic unamplified library, where the bacteria have been allowed to multiply and create additional copies of each section of the DNA.