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- PrEP = Tenofovir + Emtricitabine
- Can reduce risk of HIV acquisition by >90%, and is offered to patients at risk for new HIV Infection
- Sexual Behaviors:
- Patients with HIV-positive partner with detectable viral load
- Patients that are MSM
- Patients from high prevalence areas (e.g. sub-Saharan Africa) have have had:
- Recent bacterial STI(s)
- Sex in exchange for money
- Inconsistent condom use
- High number of partners
- Injection Drug Use:
- HIV-positive injecting partner
- Sharing of injecting equipment
- Active HIV infection
- 2-drug antiretroviral therapy would incompletely treat active HIV, and cause drug resistance
- Patients must have negative fourth-generation HIV testing and NO manifestations of acute HIV
- As well as normal renal function, and documented Hep B infection/vaccination
- Patients with chronic HBV infection can sometimes undergo combined HBV and PrEP Treatment
- q 3 mo HIV testing, as well as
- Risk-reduction counseling
- Medication adherence/side-effect assessment
- Regular Cr levels and screen for bacterial STIs
