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ID Board Review/Immunocompromised Host

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Primary Immunodeficiency

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  • Anatomic lesions
  • Lymphocyte defects
  • Combined immunodeficiency syndromes (including severe combined immunodeficiency [SCID])
  • Phagocytes
  • Complement deficiencies
  • NK cell deficiencies

Hematologic Malignancies and Stem Cell Transplantation

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  • Infections associated with chemotherapy-induced neutropenia
  • Stem cell transplant
  • Syndromes
  • Noninfectious conditions

Solid-organ Transplantation

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  • Donor-derived infections
  • Surgical site infections
  • Hospital-acquired infection
  • Opportunistic infections
  • Noninfectious conditions

Complications of immunosuppression in non-transplant population

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This includes patients on disease-modifying agents, e.g. Tumor Necrosis Factor [TNF] blockers, Corticosteroids
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  • Bacteria
  • Fungi
  • Viruses
  • Parasites
  • Protozoa

Infection Prevention in the Immunosuppressed Host

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  • Immunizations
  • Antimicrobials
  • Environmental control
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