Radiation Oncology/Corporate/Protons
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Proton Therapy
- Please see the Protons page for links to clinical information
Associations
[edit | edit source]- Particle Therapy Cooperative Group (PTCOG)
- "An organization for those interested in proton, light ion, and heavy charged particle radiotherapy"
- National Association for Proton Therapy (NAPT)
- U.S. based, independent, non-profit, public benefit corporation
- Promotes the clinical benefits of proton beam radiation therapy for cancer patients and their families
Existing Proton Facilities
[edit | edit source]North America
- Canada
- TRIUMF - ocular diseases only
- United States
- Loma Linda
- Harvard University (Massachusetts General Hospital)
- Midwest Proton Radiotherapy Institute
- MD Anderson Cancer Center
- University of California San Francisco/University of California Davis - ocular diseases only
- University of Florida
- ProCure Oklahoma
- University of Pennsylvania
- Hampton University, VA
- CDH Proton Center ProCure, IL
Europe
- Belgium
- France
- Germany
- Hahn-Meitner Institut (HMI/Charite) - ocular diseases only
- Rinecker PTC
- Heidelberg HIT
- Italy
- Russia
- Sweden
- Switzerland
- United Kingdom
- Clatterbridge Center for Oncology - ocular diseases only
Asia
- China
- Japan
- Korea
Africa
- South Africa
- IThemba LABS, South Africa
Chronologic List Overview
Facility | Country | Start | Particle | Comments |
---|---|---|---|---|
Lawrence Berkeley Laboratory | USA | 1955 | Proton, Heavy Ion | |
Svedberg Laboratory | Sweden | 1957 | Proton | New facility Uppsala, 1988 |
Harvard Cyclotron | USA | 1961 | Proton | New facility in 2001 |
JINR | Russia | 1964 | Proton | New facility 1989 |
ITEP | Russia | 1969 | Proton | |
PNPI | Russia | 1975 | Proton | |
Chiba | Japan | 1979 | Proton | |
Tsukuba | Japan | 1983 | Proton | |
PSI | Switzerland | 1984 | Proton | |
JINR | Russia | 1989 | Proton | |
Uppsala | Sweden | 1989 | Proton | |
Clatterbridge | UK | 1989 | Proton | ocular only |
Loma Linda | USA | 1990 | Proton | first hospital-based |
Nice | France | 1991 | Proton | |
Orsay | France | 1991 | Proton | |
LOuvain | Belgium | 1991 | Proton | low energy only |
iTHEMBA | South Africa | 1993 | Proton | |
MPRI | USA | 1993 | Proton | |
UCSF / UC Davis | USA | 1994 | Proton | ocular only |
Chiba | Japan | 1994 | Carbon | first ion |
TRIUMF | Canada | 1995 | Proton | ocular only |
GSI | Germany | 1997 | Carbon | |
HMI | Germany | 1998 | Proton | ocular only |
NCC | Japan | 1998 | Proton | |
Hyogo | Japan | 2001 | Proton, Carbon | |
Harvard | USA | 2001 | Proton | |
Catana | Italy | 2002 | Proton | ocular only |
Shizuoka | Japan | 2002 | Proton | |
Wakasa | Japan | 2002 | Proton | |
Wanjie | China | 2004 | Proton | |
MD Anderson | USA | 2006 | Proton | |
University of Florida | USA | 2006 | Proton | |
Southern Tohoku PTC | Japan | 2008 | Proton | |
Rinecker PTC | Germany | 2009 | Proton | |
Oklahoma ProCure | USA | 2009 | Proton | |
Heidelberg HIT | Germany | 2009 | Proton/Carbon | |
University of Pennsylvania | USA | 2010 | Proton | |
Hampton University | USA | 2010 | Proton | |
CDH ProCure Chicago | USA | 2010 | Proton | |
CNAO | Italy | 2011 | Proton/(Carbon) |
Proposed Proton Facilities
[edit | edit source]United States
- Northern Illinois University, IL
- ProCure
- American Shared Hospital Services
- American Shared Hospital Services: Tufts University, MA
- American Shared Hospital Services: MD Andersen Orlando, FL
- American Shared Hospital Services: Long Beach Memorial, CA
- American Shared Hospital Services: San Francisco Bay area, CA
- American Shared Hospital Services: Kettering Medical Center, Dayton, OH
- Lehigh Valley Hospital, PA
- South Florida Proton Center, FL
- Broward Medical Center, FL
- Washington University, MO
- First Coast Oncology, FL
- McLaren Health Care, MI - ProTom
- Dayton, OH - Optivus
- University of Iowa, IA
- Scripps Health, CA - Varian
- Wright State University, OH
- Knoxville, TN
- University of Maryland, MD
- Mayo Clinics, MN and AZ
- Emory University, GA
- Atlantic Health System, NJ - ProTom
- Texas Oncology, Dallas, TX
- Willis-Knighton, Shreveport, LA (Summer 2014)
Europe
- MedAustron, Austria - proton and carbon ion
- WPE Essen, Germany
- Prague, Czech Republic
- Rozumberok, Slovakia
- Krakow, Poland
- Caen, France - carbon ion
- Dimitrovgrad, Russia
Middle East
Asia
- National Taiwan University Hospital, Taiwan
- Linkou Chang Gung Hospital, Taiwan
- Shanghai Proton and Heavy Ion Hospital
Vendors
[edit | edit source]- Hitachi and Hitachi North America
- Proton facilities: Tsukuba, MD Anderson
- IBA
- Proton facilities: Massachusetts General Hospital, National Cancer Center Japan, National Cancer Center Korea, Wanjie Proton Therapy Center, Midwest Proton Radiotherapy Institute
- Optivus Proton Therapy
- Proton facilities: Loma Linda
- Varian Medical Systems (ACCEL subsidiary)
- Proton facilities: Paul Scherrer Institute
- Siemens AG
- Still River Systems
- ProTom International
- Compact Particle Acceleration Corporation & TomoTherapy
Treatment Planning
[edit | edit source]- PerMedics Medical Systems - Odyssey
- Elekta via CMS software - XiO and Focal
Patient Positioning
[edit | edit source]- Brindisi, Italy; 2010 PMID 20465816 -- "Patient positioning in the proton radiotherapy era." (Devicienti S, J Exp Clin Cancer Res. 2010 May 13;29(1):47. [Epub ahead of print])
- Review of various robotic couch applications
Overview by Institution
[edit | edit source]- Heidelberg, Germany; 2010 PMID 20831505 -- "Heidelberg Ion Therapy Center (HIT): Initial clinical experience in the first 80 patients." (Combs SE, Acta Oncol. 2010 Oct;49(7):1132-40.)
- CNAO Italy; 2009 PMID 19579862 -- "The National Center for Oncological Hadron Therapy: status of the project and future clinical use of the facility." (Orecchia R, Tumori. 2009 Mar-Apr;95(2):169-76.)
- Overview of plans for the facility
- Hyogo Japan; 2009 PMID 19920379 -- "[Current status and future of particle radiotherapy at the Hyogo Ion Beam Medical Center]" [Article in Japanese] (Murakami M, Gan To Kagaku Ryoho. 2009 Nov;36(11):1791-4.)
- Overview. 2,639 patients treated with prostate, H&N, liver, lung and sarcomas (total 87%). Proton beam 2,122 (80%), carbon ion 517 (20%)
- European ENLIGHT network
- 2008 PMID 18208851 -- "COST-ENLIGHT strategic workshop on hadron (particle) therapy, CERN, Geneva, 3-4 May 2007." (Taylor RE, Br J Radiol. 2008 Mar;81(963):169-71. Epub 2008 Jan 21.)
- Overview of meeting to review current status of hadron therapy in Europe
- 2007 PMID 17513898 -- "European developments in radiotherapy with beams of large radiobiological effectiveness." (Amaldi U, J Radiat Res (Tokyo). 2007;48 Suppl A:A27-41.)
- Overview of European experience, including development of facilities in Heidelberg (HIT) and Pavia (CNAO). Also review of Marburg, Wiener Neustadt, Lyon and Uppsala and the development of ENLIGHT network
- 2008 PMID 18208851 -- "COST-ENLIGHT strategic workshop on hadron (particle) therapy, CERN, Geneva, 3-4 May 2007." (Taylor RE, Br J Radiol. 2008 Mar;81(963):169-71. Epub 2008 Jan 21.)
- Paul Scherrer Institut; 2007 PMID 17878101 -- "[Proton beam therapy: clinical indications and summary of the Swiss experience] - [Article in French]" (Weber DC, Bull Cancer. 2007 Sep 1;94(9):807-15.)
- Harvard
- 2007 PMID 17668954 -- "Clinical proton radiation therapy research at the Francis H. Burr Proton Therapy Center." (DeLaney TF, Technol Cancer Res Treat. 2007 Aug;6(4 Suppl):61-6.)
- Review of MGH current clinical research goals
- 1980 PMID 6245096 -- "Clinical experience with proton beam radiation therapy." (Suit HD, J Can Assoc Radiol. 1980 Mar;31(1):35-9.)
- Cannot yet assess efficacy, but results warrant further investigation
- 2007 PMID 17668954 -- "Clinical proton radiation therapy research at the Francis H. Burr Proton Therapy Center." (DeLaney TF, Technol Cancer Res Treat. 2007 Aug;6(4 Suppl):61-6.)
- Loma Linda; 2007
- 2007 PMID 17668955 -- "Development and operation of the Loma Linda University Medical Center proton facility." (Slater JD, Technol Cancer Res Treat. 2007 Aug;6(4 Suppl):67-72.)
- Overview of a hospital-based center development
- 2006 PMID 16551128 -- "Clinical applications of proton radiation treatment at Loma Linda University: review of a fifteen-year experience." (Slater JD, Technol Cancer Res Treat. 2006 Apr;5(2):81-9.)
- Review of 15 year experience using protons
- 2007 PMID 17668955 -- "Development and operation of the Loma Linda University Medical Center proton facility." (Slater JD, Technol Cancer Res Treat. 2007 Aug;6(4 Suppl):67-72.)
Other Entities
[edit | edit source]- GSI, Germany
- ProBeam Oncology, USA
- Partnership between MD Anderson Cancer Center, Sanders Morris Harris, and The Styles Company to manage the Proton Therapy Center at MD Anderson
- Proton Brotherhood of the Balloon, USA
- ProCure Treatment Centers, USA
- TERA Foundation, Italy
- Proton Therapy Global Management
- SAH Global