Radiation Oncology/Lymphoid
Appearance
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Hematologic Malignancies
Chapter Links
[edit | edit source]Indications
- Hodgkin lymphoma
- Non-Hodgkin lymphoma
- Primary CNS lymphoma
- Cutaneous lymphomas
- Leukemia
- Multiple myeloma and plasmacytoma
- Waldenstroms macroglobulinemia
- Langerhans' Cell Histiocytosis
Technique
Conceptual Simplified Classification
[edit | edit source]Lymphoid Disorders
[edit | edit source]- Acute lymphocytic leukemia (ALL)
- Chronic lymphoproliferative disorders
Myeloid Disorders
[edit | edit source]- Acute myeloid leukemia (AML)
- Chronic myeloid disorders
- Myeloproliferative disease (MPD)
- Chronic myelogenous leukemia (CML)
- Polycythemia vera
- Essential thrombocythemia
- Myelodysplastic/myeloproliferative diseases
- Myelodysplastic syndromes (MDS)
- Myeloproliferative disease (MPD)
WHO classification
[edit | edit source]Myeloid Neoplasms
[edit | edit source]- Acute myeloid leukemia (AML)
- Acute biphenotypic leukemias
- Myeloproliferative disease
- Chronic myelogenous leukemia (CML)
- Chronic neutrophilic leukemia
- Chronic eosinophilic leukemia/hypereosinophilic syndrome
- Chronic idiopathic myelofibrosis
- Polycythemia vera
- Essential thrombocythemia
- Myeloproliferative disease, unclassifiable
- Myelodysplastic/myeloproliferative diseases
- Chronic myelomonocytic leukemia
- Atypical chronic myelogenous leukemia
- Juvenile myelomonocytic leukemia
- Myelodysplastic syndromes (MDS)
- Refractory anemia
- With ringed sideroblasts
- Without ringed sideroblasts
- Refractory cytopenia
- Refractory anemia
- 5q- (5q deletion) syndrome
- Myelodysplastic syndrome, unclassifiable
Lymphoid: B-cell neoplasms
[edit | edit source]- Precursor B-cell neoplasms
- Precursor B-lymphoblastic leukemia/lymphoma
- Precursor B-cell acute lymphoblastic leukemia
- Mature (peripheral) B-cell neoplasms
- B-cell chronic lymphocytic leukemia / small lymphocytic lymphoma
- B-cell prolymphocytic leukemia
- Lymphoplasmacytic lymphoma
- Splenic marginal zone B-cell lymphoma
- Hairy cell leukemia
- Plasma cell myeloma/plasmacytoma
- Extranodal marginal zone B-cell lymphoma of MALT type
- Nodal marginal zone B-cell lymphoma
- Follicular lymphoma
- Mantle cell lymphoma
- Diffuse large B-cell lymphoma
- Burkitt lymphoma / Burkitt cell leukemia
Lymphoid: T-cell and NK-cell neoplasms
[edit | edit source]- Precursor T-cell neoplasm
- Precursor T-lymphoblastic lymphoma/leukemia
- Precursor T-cell acute lymphoblastic leukemia
- Mature (peripheral) T/NK-cell neoplasms
- T-cell prolymphocytic leukemia
- T-cell granular lymphocytic leukemia
- Aggressive NK-cell leukemia
- Adult T-cell lymphoma/leukemia (HTLV1+)
- Extranodal NK/T-cell lymphoma, nasal type
- Enteropathy-type T-cell lymphoma
- Hepatosplenic gamma-delta T-cell lymphoma
- Subcutaneous panniculitis-like T-cell lymphoma
- Mycosis fungoides / Sezary syndrome
- Anaplastic large cell lymphoma, T/null cell, primary cutaneous type
- Anaplastic large cell lymphoma, T/null ell, primary systemic type
- Peripheral T-cell lymphoma, not otherwise characterized
- Angioimmunoblastic T-cell lymphoma
Lymphoid: Hodgkin Lymphoma
[edit | edit source]- Nodular lymphocyte-predominant Hodgkin lymphoma
- Classical Hodgkin lymphoma
- Nodular sclerosis Hodgkin lymphoma (grades 1 and 2)
- Lymphocyte-rich classical Hodgkin lymphoma
- Mixed cellularity Hodgkin lymphoma
- Lymphocyte depletion Hodgkin lymphoma
Lymphoid: Posttransplant Lymphoproliferative Disorders
[edit | edit source]- Early lesions
- Reactive plasmacytic hyperplasia
- Infectious mononucleosis-like
- PTLD polymorphic
- Polyclonal (rare)
- Monoclonal
- PTLD monomorphic (classify according to lymphoma classification)
- B-cell lymphomas
- T-cell lymphomas
- Other types (rare)
Mast Cell Disorders
[edit | edit source]- Cutaneous mastocytosis
- Systemic mast cell disease (+/- skin involvement)
- Systemic mast cell disease with associated hematologic disorder (+/- skin involvement)
- Mast cell leukemia/sarcoma
Histiocytic and Dendritic Cell Neoplasms
[edit | edit source]- Macrophage/Histiocytic neoplasm
- Histiocytic sarcoma
- Dendritic-cell neoplasms
- Langerhans cell histiocytosis
- Langerhans cell sarcoma
- Interdigitating dendritic cell sarcoma/tumor
- Follicular dendritic cell sarcoma/tumor
- Dendritic cell sarcoma, not otherwise specified