Radiation Oncology/RTOG Trials/0321
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RTOG 03-21 (PROSTATE)
- Title: Phase II Trial of Combined High Dose Rate Brachytherapy and External Beam Radiotherapy for Adenocarcinoma of the Prostate
- Objective: To estimate the rate of late Grade 3 or greater genitourinary and gastrointestinal toxicity following treatment with external beam radiation therapy and high dose rate brachytherapy
- Protocol: 45 Gy EBRT (no IMRT) + 19 Gy (2 fractions) HDR boost
- Eligibility:
- (cT1c-T2c and GS 2-6 and PSA 10-20) or
- (cT3a-T3b and GS 2-6 and PSA <=20) or
- (T1c-T3b and GS 7-10 and PSA <=20)
- N0M0
- Enrollment Target: 110 patients
- Activation: July 30, 2004