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Radiation Oncology/Supportive care/Pain

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General

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  • Opioids (strong):
    • Morphine
    • Methadone
    • Oxycodone
    • Fentanyl
    • Hydromorphone (Dilaudid, Palladone)
    • Levorphanol (Levo dromoran)
    • Oxymorphone (Numorphan)
      Oral (5 mg IR q6h, 20 mg SR bid), Parenteral, Suppository (5 mg)


Neuropathic pain

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Medications:

  • Opioids:
    • Buprenorphine
    • Fentanyl
    • Levorphanol
    • Methadone
    • Morphine
    • Oxycodone
    • Tramadol - usual: 250 mg/d. Max: 400 mg/d.
  • Antidepressants:
    Block Ca-channel, Na-channel, presynaptic reuptake inhibition of monoamines, NMDA receptor blockade
    • Tricyclic antidepressants (TCA)
    • Selective noradrenaline serotonin reuptake inhibitors (SNRI)
      Venlafaxine (Effexor) and duloxetine (Cymbalta)
  • Gabapentin (Neurontin)
    • Pregabalin (Lyrica)


References

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  • PMID 17131133, Davis MP, "What is new in neuropathic pain?" Support Care Cancer. 2006 Nov 28</ref>